A genuinely distinctive, well-styled SUV pairing the strong VQ35 V6 with Nissan's CVT — the engine itself is a real strength, but the transmission's documented concerns apply in full here.
The Murano's SUV body is a comfortable, unstressed load for this strong V6 — the same well-regarded engine found across Infiniti's lineup and the related Maxima, here paired with a CVT rather than a conventional automatic.
Unlike the Maxima covered elsewhere, this SUV uses Nissan's CVT, which means the transmission page's checklist applies here just as fully as it does on the Altima or Rogue, despite the strong engine underneath.
This is about the car itself — for engine-specific failure points, see the dedicated engine page below.
This Murano's strong 3.5L VQ35DE V6 is paired with Nissan's CVT, covered in detail on its own dedicated page under Infiniti — essential reading despite the engine's own strong reputation.
FULL ENGINE BREAKDOWNInfiniti/Nissan CVT (Jatco) — Reliable or Not →Test drive extensively under both light and firmer acceleration, feeling specifically for shudder or hesitation, and watch the temperature gauge for any unusual behaviour.
Ask whether a transmission fluid service has ever been performed, and treat an unserviced example as a candidate for proactive service.
Separately, ask for documented oil change history for the engine, since this high-revving V6 rewards consistent maintenance.